Limb Regeneration

Morphological and Cellular Aspects of Tail and Limb Regeneration in Lizards: A Model System With Implications for Tissue Regeneration in Mammals (Advances in Anatomy, Embryology and Cell Biology)
$129.00
The present review deals with the analysis of the cytological processess occurring during tissue regeneration in the tail and limb of lizards. These reptiles are considered as a model to understand the process of tissue regeneration in all amniotes. The review begins with some evolutive considerations on the origin of tail regeneration in comparison to the failure of limb regeneration, a unique case among amniotes. The formation of the tail in the embryo and the possible accumulation of stem cells in autotomous planes of the tail are discussed. The histological and ultrastructural processess occuring during blastema formation and tail regeneration and during limb cicatrization are presented. The comparison stresses the scarse to absent inflammatory reaction present in the tail vs the massive inflammatory response in the limb leading to scarring. In fact the experimental induction of a strong inflammation in the tail also leads to scarring. The importance of the nervous system in stimulating tail regeneration in lizards is emphasized. The presence of growth factors and extracellular matrix proteins during wound healing of the tail and limb is introduced. The review concludes stressing the importance of the lizard model of tissue regeneration for medical studies and applications.

Limb Regeneration (Developmental and Cell Biology Series)
$99.00
The complex phenomenon of limb regeneration that occurs in some Amphibia involves unique molecular and cellular mechanisms. When a limb is amputated a new one is produced by the transformation of the remaining adult limb tissues into an embryonic-like cell mass, called the blastema. The blastema has the ability to subsequently redifferentiate into the various tissues that comprise a limb and therefore replace the lost part. Some scientists argue that the same processes that are encountered in normal embryogenesis are reinitiated during regeneration. This is the first book that describes and analyzes the mechanisms of both limb regeneration and patterning by incorporating the information obtained from older experiments with the many new advances in molecular and cellular biology that have occurred in recent years.

Limb Lengthening and Reconstruction Surgery
$329.95
An illustrative and in-depth overview of the many available applications and techniques for limb lengthening and reconstruction, this guide provides step-by-step details on the latest surgical procedures for the correction of limb deformities due to congenital defects, growth disturbances, infection, and trauma in both children and adults. Supplying effective surgical approaches, technical tips, methods to manage complications, and clinical case studies in each chapter, this guide will be a constant companion for all orthopedic, reconstructive, pediatric, foot, ankle, upper extremity, tumor, and trauma surgeons.